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The redox signal transduction cascade is a highly complex and coordinated system involving the generation of reactive oxygen species, the oxidation of redox-relay molecules or direct oxidation of sensor molecules with thiol switches like Kelch-like ECH-associated protein 1 (Keap1), and effector molecules that change activity, localization, protein-protein interactions, or protein turnover in response to the redox signaling cascade [6, 7]

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In inflammatory bowel disease models including ulcerative colitis and cysteamine-induced colitis, BPC-157 reduces inflammatory markers (IL-6, TNF-, IL-1), improves mucosal architecture, and accelerates healing of damaged intestinal tissue

These formulations not only help limit the contact of refluxed acid and pepsin with the epithelial cells 97 but also serve as a vehicle to deliver drugs locally within the esophagus